10 Supplements to Boost Dopamine in Your Brain

Dopamine is a chemical that plays a role in regulating cognition, memory, attention and learning within your brain. It also helps regulate sleep and thinking. In normal circumstances, the nervous system of the body manages the development of dopamine. Luckily, there are some supplements that can boost dopamine levels.

1. Oregano Oil

Oregano oil has different antioxidant and antibacterial properties such as carvacrol. One study showed that consumption of carvacrol stimulated the development of dopamine in mice.

The mice study found that supplements with the oregano extract reduced dopamine degradation and caused positive behavioral effects.

While such animal studies are promising, we need further human studies to determine whether oregano oil has similar effects on humans.

2. Green Tea

Because of its antioxidant properties and nutrient content, green tea has been praised. It also contains the L-theanine amino acid, which has a direct effect on your brain.

L-theanine will increase some of your brain’s neurotransmitters like dopamine. Multiple studies have shown that L-theanine can boost the development of dopamine, which results in an antidepressant effect.

Studies show that both green tea extract and green tea as a drink will increase dopamine production.

3. Fish Oil

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Fish oil supplements (omega-3) contain two types of fatty acids:

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Several studies show fish oil supplements have antidepressant effects.

One rat study showed that a fish-oil-enriched diet increased dopamine levels by 40 percent in the brain’s frontal cortex.

Nevertheless, we need more human-based research to make a conclusive decision.

4. Ginseng

The Chinese use ginseng since ancient times as a traditional medicine.
Studies have shown that ginseng can improve brain skills, including mood, behavior, and memory.

Several animals and test-tube studies show these benefits are because of the ability of ginseng to boost dopamine levels.

It has also been proposed that some ginseng ingredients, such as ginsenosides, are responsible for increased brain dopamine, including cognitive function and focus.

One research on attention-deficit hyperactivity disorder (ADHD) in children showed that lower dopamine levels were associated with ADHD symptoms.

The children involved in the study received 2,000 mg of Korean red ginseng daily for eight weeks. The results showed that ginseng has an increased concentration in ADHD children.

Nonetheless, we need more studies to draw definite conclusions about how much ginseng improves the development of dopamine and the functioning of the brain in humans.

Related: 6 Amazing Health Benefits Of Ginseng Backed By Science

5. Curcumin

The active ingredient in turmeric is curcumin. Curcumin comes in forms such as syrup, tea, extract, and powder. They believe that it has antidepressant effects, as it improves dopamine release.

A small, controlled study found that taking 1 gram of curcumin had similar effects as Prozac medicine. Improving mood in people with major depressive disorder (MDD).

There is also evidence that curcumin increases levels of dopamine in mice.

Nonetheless, we need further research to understand the role of curcumin in increasing dopamine in humans and its use in depression management.

6. Probiotics

Probiotics, also known as good gut bacteria, not only benefit the health of the gut, but can also prevent or treat various health problems, including mood disorders.

While harmful gut bacteria can diminish the development of dopamine, probiotics can increase it, which can improve mood.

Several rats’ studies show that probiotics can boost the production of dopamine and improve mood and anxiety.

In addition, one study in people with irritable bowel syndrome (IBS) showed that those who received probiotic supplements had a reduction of symptoms of depression relative to those who received a placebo.

Although probiotic research is progressing, we need more human studies to better understand the effect of probiotics on the mood and development of dopamine.

By consuming fermented food products such as yogurt or kefir, or by taking a dietary supplement, you can easily add probiotics to your diet.

7. Vitamin D

In your body, vitamin D has many functions, including controlling neurotransmitters such as dopamine.

In one animal study, dopamine levels increased when supplemented with vitamin D3.

Because of limited research, it is hard to say whether vitamin D supplementation would boost dopamine levels.

Some animal studies are promising, but we need more human studies to understand the relationship between vitamin D and dopamine.

8. Caffeine

Studies have found that caffeine can boost cognitive function by increasing neurotransmitter releases such as dopamine.

Caffeine can improve brain function by raising the dopamine receptor levels in your brain.

Your body will establish caffeine tolerance, however, meaning it will learn how to handle increased amounts.

Thus, you can consume more caffeine than you did before, to experience the same effects.

9. Magnesium

Magnesium plays a vital role in ensuring a healthy body and mind. Its antidepressant properties are not yet fully understood. Therefore, there is evidence that magnesium deficiency may contribute to lower dopamine levels.

Furthermore, one study showed that magnesium supplementation increased dopamine levels and had antidepressant effects on mice.

Studies on the impact of magnesium supplements on dopamine concentrations are limited to animals.

However, if you can not get enough magnesium from your diet alone, it may be a superb idea to take a supplement to ensure that you fulfill your requirements.

10. Berberine

Berberine is an active component present in some plants and herbs and is extracted from them. It has been used for hundreds of years in traditional Chinese medicine and has become popular as a natural supplement recently.

Several animal studies show that berberine may boost the levels of dopamine and can fight depression.

There are no reports that berberine supplements affect dopamine levels in humans. Therefore, we need further research.

Other Supplements

  1. Rhodiola Rosea: Rhodiola is the root and the scientific name is Rhodiola Rosea. The root contains over 140 active ingredients. Russian people have been using Rhodiola for centuries to treat anxiety, fatigue, and depression.
  2. Bacopa monnieri: Brahmi is a staple plant in the traditional Ayurvedic medicine known as Bacopa monnieri. For centuries, Ayurvedic physicians have used Bacopa monnieri for a variety of purposes, including memory recovery, anxiety reduction, and epilepsy.
  3. Echinacea tea: Echinacea was tested and found to be effective as an anti-anxiety supplement. The extract helps to control the synapses that enable the body and brain to communicate.
  4. Maca Root: Maca root can improve brain function. In fact, people in Peru have been using it to improve the performance of children in school for many decades. Studies in animals with a damaged memory show an increase in learning and memory. Black Maca appears to be more successful in this respect than other varieties.

Bottom Line

Some medical conditions and diet and lifestyle decisions can lower the levels of dopamine. Along with eating a balanced diet, many supplements can help boost the levels of dopamine. Speaking to your health care provider or registered dietitian is always the best way to determine whether certain supplements are right for you.

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References

Antidepressant-like effect of carvacrol (5-Isopropyl-2-methylphenol) in mice: involvement of dopaminergic system. Fundam Clin Pharmacol. 2011.

Monoamine reuptake inhibition and mood-enhancing potential of a specified oregano extract. Br J Nutr. 2011.

L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008.

Green tea consumption is associated with depressive symptoms in the elderly. Am J Clin Nutr. 2009.

A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids. J Clin Psychiatry. 2007.

Dietary fish oil affects monoaminergic neurotransmission and behavior in rats. J Nutr. 1998.

Modulatory effect of ginseng total saponin on dopamine release and tyrosine hydroxylase gene expression induced by nicotine in the rat. J Ethnopharmacol. 2000.

Korean Red Ginseng protects dopaminergic neurons by suppressing the cleavage of p35 to p25 in a Parkinson’s disease mouse model. J Ginseng Res. 2015.

Protective effects of ginseng on neurological disorders. Front Aging Neurosci. 2015.

Clinical effects of korean red ginseng on attention deficit hyperactivity disorder in children: an observational study. J Ginseng Res. 2011.

Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Phytother Res. 2014.

The effects of curcumin on depressive-like behaviors in mice. Eur J Pharmacol. 2005.

Bacterial neuroactive compounds produced by psychobiotics. Adv Exp Med Biol. 2014.

Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-alpha, interleukin-1beta, and nitric oxide. Brain Res Dev Brain Res. 2002.

Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome. Gastroenterology. 2017.

Vitamin D signaling and the differentiation of developing dopamine systems. Neuroscience. 2016.

Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain. Transl Psychiatry. 2015.

Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Prog Neuropsychopharmacol Biol Psychiatry. 2009.

Berberine alleviates symptoms of anxiety by enhancing dopamine expression in rats with post-traumatic stress disorder. Korean J Physiol Pharmacol. 2018.

Berberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responses. J Neuroimmunol. 2015.

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Naeem Durrani BSchttps://defatx.com/
Naeem is a freelance medical and nutrition writer. His interests include medical research, and the scientific evidence around effective wellness practices, which empower people to transform their lives.
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