5 Best Supplements for Neuropathy Complications

best supplements for neuropathy

Neuropathy is a term that describes nerve-affecting disorders that can cause unpleasant or painful symptoms. Neuropathy is a complication of diabetes or a common side effect of chemotherapy. There are traditional therapies for the diagnosis of neuropathy. Here are 5 best supplements for neuropathy complications.

1. Fish Oil Supplements for Neuropathy

Because of its anti-inflammatory properties and its ability to repair nerves, fish oil is useful in treating neuropathy. It also helps relieve discomfort and muscle soreness. It is available in the optional form. You can take between up to 5,400 mg a day.

As a cure for diabetic peripheral neuropathy, a study explored the potential for fish oil. Studies have shown that fish oil can slow the progression of diabetic neuropathy and even reverse it. The anti-inflammatory effects help to reduce pain and discomfort (1).

The neuroprotective effects can help stimulate the outgrowth of neurons. While the results are encouraging to elaborate on these findings, we need more studies.

2. Vitamins B Complex for Neuropathy

B vitamins are useful because they promote the safe functioning of the nervous system. Vitamin B deficiency also triggers peripheral neuropathy. Vitamin B-1 (thiamine and benfotiamine), B-6, and B-12 should be included.

Benfotiamine is like vitamin B-1, also known as thiamine. Therefore, it is efficient in reducing pain, inflammation, and avoiding cell damage. One cause of peripheral neuropathy is a deficiency of vitamin B-12. Vitamin B-12 deficiency can cause permanent nerve damage when left untreated.

Vitamin B-6 can help to keep the nerve protected. But you need not take over 200 milligrams (mg) of B-6 per day. Getting higher amounts can also cause damage to the nerves and cause neuropathic symptoms.

Research suggests that vitamin B supplementation can facilitate nerve repair. This may be because B vitamins can promote the regeneration of nerve tissue and enhance nerve function (2).

B vitamins can help relieve pain and inflammation. These studies showing the value of benfotiamine mixed in the treatment of neuropathy. Benfotiamine has a positive effect on diabetic neuropathy (3, 4).

The above studies show that discomfort was reduced, and the condition improved. But a small study found that people with type 1 diabetes who took 300 mg of benfotiamine a day showed no significant nerve function or inflammation improvements (5).

3. Curcumin Supplements for Neuropathy

Curcumin is a herb best known for its properties like anti-inflammatory, antioxidant, and analgesic. It can help relieve tingling and numbness in your hands and feet.

It is available in the additional forms, and you can take 1 teaspoon 3 grams of turmeric powder with 1/4 teaspoon ground pepper. Therefore, you can add turmeric to tea, foods like curries, egg salads, and smoothies.

An animal study in mice that took for 14 days, curcumin decreased chemotherapy-induced neuropathy. It had a positive impact on pain, swelling, and loss of function (6).

The levels of antioxidants and calcium have improved. However, to expand on these results, we need greater human studies.

4. Alpha-Lipoic Acid Supplements for Neuropathy

Alpha-lipoic acid is an antioxidant that can be effective in the treatment of diabetes and cancer-induced neuropathy. It can reduce blood sugar levels, enhance nerve function, and ease painful symptoms in the legs and arms such as discomfort, itching, tingling, prickling, numbness, and burning. In capsule form, you can take up to 1,200 mg per day.

Alpha-lipoic acid has a positive effect on the conduction of nerves and decreased neuropathic pain. A small study shows that alpha-lipoic acid is useful in protecting people from diabetic neuropathy and oxidative damage (7).

5. Acetyl-L-Carnitine Supplements

Acetyl-L-carnitine is an antioxidant and amino acid. In addition, it can increase levels of energy, create healthy nerve cells, and reduce neuropathic pain.

A standard dose is 500 mg twice daily. According to the study, peripheral neuropathy, cancer-associated fatigue, and physical conditions were improved by acetyl-L-carnitine (8).

Participants had 3 grams of acetyl-L-carnitine per day for 8 weeks. They observed significant differences in just 12 weeks between the groups.

The Bottom Line

Please talk to your doctor before you begin any new medications or change your treatment plan. Therefore, we do not intend these supplements to replace any treatment plan approved by the health care providers. However, such supplements may be superior to other treatment options, as they have fewer side effects. In other ways, these supplements can also support your health and well-being.

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Naeem Durrani BSc
Naeem Durrani is a freelance journalist who specializes in health and wellness innovation. His interests include medical research, nutrition, and the scientific evidence around effective wellness practices that empower people to positively transform their lives.
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